The multifrequency electrical impedance mammograph (MEM) principle of operation is based on the method of electrical impedance tomography (EIT). The present device has come to replace the previously developed single-frequency device MEIK.
Various organs and tissues in a human body possess different electrical properties. For instance, it is a well-known fact that many tumours, in particular malignant breast tumours, feature electrical conductivity (ability to conduct electrical current), which differs considerably from the electrical conductivity of surrounding healthy tissues. The MEM makes it possible to obtain the picture of biological tissues electrical conductivity distribution in the breast in its transverse sections and locate such tumours in the obtained images.
Impedance Medical Technologies Company (IMT, LLC) develops and manufactures medical diagnostic instruments based on the method of electrical impedance tomography (EIT). Visualization of the spatial distribution of the electrical properties of tissues and organs opens a new channel for obtaining information about their condition without the use of ionizing radiation and, in combination with other diagnostic methods, significantly improves the accuracy of diagnosis of diseases, allowing to detect them at the earliest stages. The method of electrical impedance tomography makes it possible to carry out both visual and quantitative assessment of the tissue. In particular, produced by the Company Multi-frequency Electrical Impedance Mammograph "MEM" enables detection of early stages of development of malignant tumors (Se = 76%, Sp = 75%), and diagnosing of benign diseases (mastopathy, mastalgia, etc.). Unlike other imaging techniques (X-ray, ultrasound, MRI, etc.), which reflect the mechanical density of tissues, multi-frequency electrical impedance tomography allows us to study their physiological condition due to the high correlation of the electrical properties of tissues with the state of cell membranes and intercellular space.
Creation of new instruments was made possible due to scientific developments, performed at the Kotel'nikov Institute of Radio Engineering and Electronics of the Russian Academy of Sciences, as well as medical research and clinical trials carried out at Yaroslavl State Medical Academy and the Russian Research Center of Radiology. This helps us to make our technologies in the field of electrical impedance tomography leading in the world now. Inventions, which formed the basis of instruments, won gold and silver medals at International Salon of Inventions and Innovations "Eureka" (Brussels), "Archimedes" (Moscow) and many diplomas. The results of the research and medical tests were published in leading international and Russian journals.
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